Catalog No. : PLS-614
Product Name : HS-PEG-SH, MW 5k
Description :

HS-PEG-SH is a linear homobifunctional PEG with two reactive free thiol, SH, sulfhydryl, or mercapto groups that selectively react with maleimide and transition metal surface including gold, silver, etc. HS-PEG-SH can be easily air oxidized and polymerized via S-S disulfide bonds, which can be reversed with reducing agents. It is a useful reagent for reversible crosslinking PEGylation.


1. Injectable laminin-functionalized hydrogel for nucleus pulposus regeneration, Biomaterials, 2013 (34): 7381-7388, Text.

2. Ultralow protein adsorbing coatings from clickable PEG nanogel solutions: Benefits of attachment under salt-induced phase separation conditions and comparison with PEG/albumin nanogel coatings.  Langmuir 29.12 (2013): 4128-4139. Text.

3. Clickable Poly (ethylene glycol)‐Microsphere‐Based Cell Scaffolds. Macromolecular chemistry and physics 214.8 (2013): 948-956. Text.

4. Design of interpenetrating chitosan and  poly(ethylene glycol) sponges for potential drug delivery applications, Carbohydrate Polymers, 2017, Pages 166-175, Text.

5. Time-Controllable Lipophilic-Drug Release System Designed by Loading Lipid Nanoparticles into Polysaccharide Hydrogels, Macromolecular Biosciences, Issue 9, 2017, 1700045, Text.

6. Effect of end-grafted polymers conformation on protein resistance. Langmuir. 2018 Jan 12. Text.

7. Synthetic hydrogels formed by thiol–ene crosslinking of vinyl sulfone-functional poly (methyl vinyl ether-alt-maleic acid) with α, ω-dithio-polyethyleneglycol. Soft Matter. 2018. Text.

8. Opposing temperature dependence of the stretching response of single PEG and PNiPAM polymers, J. Am. Chem. Soc.2019, Text.

9. Engineered 3D hydrogels with fibronectin that sequester and present growth factors, Biomaterials, 2020, Text.

10. A Rapid Crosslinkable Maleimide-Modified Hyaluronic Acid and Gelatin Hydrogel Delivery System for Regenerative Applications, Gels, 2021, 7(1), 13, Text.

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